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Travel Vaccines and Prophylactic therapy

TwinrixUse: Active immunisation against hepatitis A and hepatitis B virus infection
Adverse Reactions: Local soreness and redness; fatigue; headache; malaise; nausea; others.
1st dose at elected date, 2nd dose 1 month later, 3rd dose 6 months after 1st dose
HavrixUse: Active immunisation against hepatitis A virus infection in susceptible individuals > 15 years
Adverse Reactions: Local soreness, induration, redness, swelling; headache; malaise; fever; nausea, loss of appetite;
Interactions: Hepatitis A virus immune serum globulin
1 mL dose IMI into deltoid +/- booster dose 6-12 months later
Typhim ViUse: Active immunisation against typhoid fever in adults and children greater than or equal to 2 years
Adverse Reactions: Local reactions; fever, headache, malaise, fatigue, joint pain, myalgia, GI upset; others.
Interactions: Other vaccines (admin at separate sites)
0.5 mL IMI, greater than or equal to 2 weeks prior to possible exposure.
VivaximUse: Active immunisation against hepatitis A and Typhoid fever infection
1 ML dose at least 14 days before to possible exposure
A bosster for Hep A in 6 to 12 months later to long term (>10yrs) cover for Hep A
Doryx***Pregnancy Category D
Use: Infections due to susceptible organisms; malaria prophylaxis (in combination with other agents
Contraindications: Concomitant vitamin A, retinoids; pregnancy, lactation, children
Precautions: Renal impairment; venereal disease; prolonged use
Adverse Reactions: Photosensitivity; superinfection; pseudomembranous colitis; GI disturbances; others.
Interactions: Anticoagulants; penicillins; antacids; iron preps; vitamin A, retinoids; barbiturates; anticonvulsants;
100 mg/day; commence 2 days prior to entering a malarious area, continue whilst there and for 2 weeks after leaving malarious area; max. 8 weeks therapy;
[Should be taken with food.]
Mencevax ACWYUse: Active immunisation against meningococcal meningitis (groups A, C, W135, Y) in adults, children > 2 years
Precautions: Impaired immune response; acute malaria; pregnancy, lactation
Adverse Reactions: Local reactions; lymphadenopathy; fever; URT illness; fatigue; malaise; headache; increased
meningococcal carriage rates; neurological reactions
0.5 mL SCI.
Stamaril Pregnancy Category B2
Use: Immunisation against yellow fever
Contraindications: Hypersensitivity to poultry products; acute febrile, chronic disease; immunodeficiency;
generalised malignancies; IV admin; infants < 6 months
Precautions: Pregnancy; children 6-12 months
Adverse Reactions: Local induration, redness, haematoma; asthenia; fever; headache; myalgia
Adults, children > 6 months: 0.5 mL (reconstituted vaccine) SCI or IMI provides protection for life.


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